EINECS:261-685-1
Molecular Formula:C₈H₁₁N₅O₃
Synonyms:aciclovir; Acyclovir (Patented-No Supply); N(9)-Oxyethoxymethylguanine (Acyclovir); Acyclovir; 9-[(2-Hydroxyethoxy)methyl]guanine
Molecular Structure:
Appearance:White to light yellow crystal powder
Molecular Weight:225.20464
Density:1.77
Boiling Point:595 °C at 760 mmHg
Melting Point:256-257℃
Flash Point:595 °C at 760 mmHg
Storage Temperature:20°C
Solubility:Water solubility: 0.7 mg/mL
Biological Activity:Antiviral agent, active against herpes simplex viruses HSV-1 and HSV-2 (EC 50 values are 0.85 and 0.86 μ M respectively). Interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate. Induces apoptosis in cells transfected with HSV-TK (suicidal gene therapy).
Stability:Stable. Incompatible with strong oxidizing agents.
Usage:Orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Antiviral