Molecular Formula: C₁₅H₂₃ClN₂O
Synonyms: Cyclopropanecarboxamide,2-(aminomethyl)-N,N-diethyl-1-phenyl-, monohydrochloride, (1R,2S)-rel- (9CI); Milnacipran HCl; Cyclopropanecarboxamide, 2-(aminomethyl)-N,N-diethyl-1-phenyl-,monohydrochloride, cis-; Dalcipran; F 2207; Ixel; Cyclopropanecarboxamide,2-(aminomethyl)-N,N-diethyl-1-phenyl-, hydrochloride (1:1), (1R,2S)-rel-; Toledomin;
Appearance: White crystalline powder
Molecular Weight: 282.80892
Boiling Point: 393 °C at 760 mmHg
Melting Point: 179-181°C
Flash Point: 393 °C at 760 mmHg
Storage Temperature: 2-8°C
Solubility: 19 mg/mL in water
Biological Activity: Orally active 5-HT and noradrenalin re-uptake inhibitor (SNRI) (IC 50 values are 203 and 100 nM respectively) that displays no affinity at a range of other receptors. Causes adaptive changes to α 1 -adrenergic and 5-HT 2A serotonergic systems when administered repeatedly. Exhibits antidepressive and antinociceptive activities in vivo .
Usage: Antidepressant