Molecular Formula: C₂₂H₂₃ClN₂O₂
Synonyms: Sch 29851; Bedix Loratadina; Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylate; Claratyne; Biloina; Histaloran; Lorastine; Alarin; Loratadine (JAN/USAN); Loratadina [Spanish]; Loradif; Claritin D; Sensibit; Loranox; 1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-, ethyl ester; Sohotin; Clarityne; Fristamin; Bonalerg; Aerotina; Claritin; Rhinase; Alerpriv; Lertamine; Allertidin; Loratadine (79794-75-5); Loratadina; Clarityne-D; Lorantis; Pylor; Lowadina; Lesidas; Loratyne; Tadine;
Appearance: White powder
Molecular Weight: 382.88322
Density: 1.261 g/cm3
Boiling Point: 531.3 oCat 760 mmHg
Melting Point: 134-136 oC
Flash Point: 275.1oC
Storage Temperature: 2-8°C
Solubility: Insoluble
Biological Activity: Peripheral histamine H 1 receptor antagonist (K i = 35 nM); devoid of central effects. Orally active antiallergic agent.
Stability: Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents.
Usage: A nonsedating-type histamine H1-receptor