Molecular Formula: C₂₂H₂₂ClKN₆OK
Synonyms: Lotim; L-158086; Ocsaar; Losacor; Tenopres; Lortaan; Losaprex; Hyzaar; Niten; DuP 753; Losartan monopotassium salt; MK 954; Lorzaan; Cozaar; Llosartan; Losartanpotassium; Lorzaar; 1H-Imidazole-5-methanol,2-butyl-4-chloro- 1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]- methyl]-,monopotassium salt; 2-Butyl-4-chloro-1-(2-(tetrazol-5-yl)biphenyl-4-ylmethyl)-1H-imidazole-5-methanol potassium; MK-0954; Losacar; MK 0954; potassium [2-butyl-5-chloro-3-[[4-[2-(2,3,4-triaza-1-azanidacyclopenta-2,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol; Cozaar (TN);
Appearance: white to off-white crystalline powder
Molecular Weight: 461.01
Boiling Point: 682 °C at 760mmHg
Melting Point: 183.5-184.5 deg C /Losartan/
Flash Point: 366.3 °C
Solubility: Freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone.
Biological Activity: Selective non-peptide angiotensin AT 1 receptor antagonist. Inhibits the contractile effects of angiotensin II on rabbit aorta and jugular vein (pA 2 = 8.27). Orally active antihypertensive agent.
Usage:  Losartan potassium (CAS NO.124750-99-8) can be used as a nonpeptide angiotensin II AT1-receptor antagonist.