Molecular Formula: C₂₆H₃₇N₅O₂
Synonyms: Ergoline-8-carboxamide,N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-, (8b)- (9CI); Cabaser; Cabaseril; 1-((6-Allylergolin-8beta-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea; Ergoline-8beta-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-;
Appearance: White Crystalline Solid
Molecular Weight: 451.60428
Density: 1.156 g/cm3
Melting Point: 102-104°C
Storage Temperature: Store at +4°C
Refractive index: 1.594
Solubility: Insoluble in water
Biological Activity: Selective D 2 -like dopamine receptor agonist (K i values are 0.7, 1.5, 9.0 and 165 nM for D 2 , D 3 , D 4 and D 5 receptors respectively) that also displays high affinity for several serotonin receptor subtypes (K i = 1.2-20.0 nM for 5-HT 1A , 5-HT 1D , 5-HT 2A and 5-HT 2B ). Inhibits secretion of prolactin and growth hormone and reverses levodopa-induced dyskinesias in Parkinsonian monkeys.
Usage: A dopamine D2-receptor agonist