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EINECS: 253-819-2
Molecular Formula: C20H17FO3S
Synonyms: 1H-Indene-3-aceticacid, 5-fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-, (Z)-; (Z)-5-Fluoro-2-methyl-1-[p-(methylsulfinyl)benzylidene]indene-3-acetic acid; Aflodac; Arthrocine; Artribid; Clinoril; Clisundac; Imbaral; MK 231; Mobilin; Reumofil; Reumyl; Sudac;
Appearance: Yellow solid.
Molecular Weight: 356.41
Density: 1.38 g/cm3
Boiling Point: 581.6 °C at 760 mmHg
Melting Point: 182-185°C
Flash Point: 305.6 °C
Storage Temperature: Keep tightly closed.
Refractive index: 1.672
Solubility: Soluble in DMSO or aqueous bases.
Biological Activity: Prodrug. Metabolizes to sulindac sulfide, a cyclooxgenase inhibitor that represses ras signaling, and sulindac sulfone, an antitumor agent, following oral administration in vivo . Widely used anti-inflammatory agent.
Stability: Stable at normal temperatures and pressures.
Usage: A non-steroidal anti-inflammatory agent. An anti-inflammatory
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