EINECS: 213-496-0
Molecular Formula: C₁₂H₂₀N₂O₃S.HCl
Synonyms: Methanesulfonamide,N-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-, monohydrochloride(9CI); Methanesulfonanilide, 4'-[1-hydroxy-2-(isopropylamino)ethyl]-,monohydrochloride (8CI); β-Cardone; 4'-[1-Hydroxy-2-(isopropylamino)ethyl]methanesulfonanilide hydrochloride; 4'-[2-(Isopropylamino)-1-hydroxyethyl]methanesulfonanilide hydrochloride; 4'-[2-(Isopropylamino)-1-hydroxyethyl]methanesulfonanilide monohydrochloride; Betapace; DL-MJ 1999; Darob; MJ 1999; N-Isopropyl-b-(4-methanesulfonamidophenyl)ethanolaminehydrochloride; Sotacor; Sotalex; Sotalol HCl; Sotalol hydrochloride; dl-Sotalolhydrochloride;
Appearance: white to off-white powder
Molecular Weight: 308.82474
Boiling Point: 443.3 °C at 760 mmHg
Melting Point: 218-220°C
Flash Point: 221.9 °C
Storage Temperature: Store at RT
Solubility: Soluble in water: 20 mg/mL
Biological Activity: A relatively potent pure β adrenergic antagonist, unique in possessing additional class III antiarrhythmic activity. Also available as part of the Mixed Adrenergic Tocriset™ .
Usage: A potent -adrenergic receptor antagonist. A class III antiarrythmic. It has been shown to prolong action potential and increases the refractory period