Product name |
Pranlukast |
CAS No. |
103177-37-3 |
Molecular Structure |
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Uasage |
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EINECS: 201-616-4
Molecular Formula: C27H23N5O4
Synonyms: Benzamide,N-[4-oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl]-4-(4-phenylbutoxy)- (9CI); 4-Oxo-8-[4-(4-phenylbutoxy)benzoylamino]-2-(tetrazol-5-yl)-4H-1-benzopyran; 8-[4-(4-Phenylbutoxy)benzoyl]amino-2-(5-tetrazolyl)-4-oxo-4H-1-benzopyran; Azlaire; CCN 00401; ONO 1078; ONO-RS 411; Onon; RS 411; SB 205312;
Appearance: off-white solid
Molecular Weight: 481.5
Density: 1.374g/cm3
Boiling Point: °Cat760mmHg
Melting Point: 236-238°C
Refractive index: 1.68
Biological Activity: Selective cysteinyl leukotriene receptor 1 (CysLT 1 ) antagonist (IC 50 values are ~ 4-7 and 3620 nM for CysLT 1 and CysLT 2 respectively). Inhibits contraction of airway smooth muscle, microvascular leakage into airways and eosinophil infiltration. Can decrease symptoms of bronchial asthma.
Usage: A potent, selective and orally active CysLT receptor antagonist. Leukotriene antagonist. Used as an antiasthmatic
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