|
Molecular Formula: C12H10F3N3O4
Synonyms: 2,4-Imidazolidinedione,5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-; 1-(3-Trifluoromethyl-4-nitrophenyl)-4,4-dimethylimidazolidine-2,5-dione; 1-(3-Trifluoromethyl-4-nitrophenyl)-4,4-dimethylimidazoline-2,5-dione; Anandron; Nilandron; Nilandrone; RU 23908; RU 23908-10;
Appearance: Crystalline Solid
Molecular Weight: 317.22071
Density: 1.463 g/cm3
Melting Point: 149 °C
Storage Temperature: Store in original container in a cool dark place.
Solubility: Insoluble in water
Biological Activity: Non-steroidal and silent antiandrogen. Binds to androgen receptors and also inhibits androgen biosynthesis in vitro . In rats in vivo it inhibits androgen-induced prostate weight increase and inhibits negative androgen-dependent gonadotropin feedback leading to an increase in luteinising hormone and testosterone. Orally active.
Usage: Nonsteroidal antiandrogen. Antineoplastic (hormonal)
|
首页
.png)
