Product name |
Nilotinib |
CAS No. |
641571-10-0 |
Molecular Structure |
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Uasage |
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Molecular Formula: C28H22F3N7O
Synonyms: 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide; 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl]benzamide; AMN-107; AMN107; Benzamide, 4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(4-(3-pyridinyl)-2-pyrimidinyl)amino)-; AMN 107; Nilotinib(TINIBS ); Nilotinib & its intermediates; Nilotinib hydrochloride monohydrate;
Appearance: Off-White Solid
Molecular Weight: 529.52
Density: 1.36 g/cm3
Refractive index: 1.65
Usage: Nilotinib (CAS NO.641571-10-0) is used in treatment of leukemia (specifically chronic myeloid leukemia). In that study 92% of patients (already resistant or unresponsive to Gleevec) achieved a normal white blood cell counts after five months of treatment. The drug carries a black box warning for possible heart complications.
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