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   Aprepitant

Product name	Aprepitant
CAS No.	170729-80-3
Molecular Structure
Uasage
Molecular Formula:C23H21F7N4O3 Synonyms:3H-1,2,4-Triazol-3-one,5-[[2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-,[2R-[2a(R*),3a]]-; Emend; L 754030; MK 0869; MK 869; ONO7436; Appearance:Off-White to Light Yellow Cyrstalline Solid Molecular Weight:534.43 Density:1.51 g/cm3 Refractive index:1.564 Usage:A novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2

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