EINECS: 200-089-8
Molecular Formula: C₁₁H₁₈ClNO₃
Synonyms: 1,2-Benzenediol,4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, hydrochloride (9CI); Benzylalcohol, 3,4-dihydroxy-a-[(isopropylamino)methyl]-, hydrochloride (8CI); Protocatechuyl alcohol, a-(isopropylaminomethyl)-,hydrochloride (5CI); 1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol hydrochloride; 3,4-Dihydroxy-a-(isopropylaminomethyl)benzylalcohol hydrochloride; Aerolone; Aerotrol; Asthpul; DL-Isoprenalinehydrochloride; DL-Isoproterenol hydrochloride; Euspiran; Isadrine; Isomenyl; Isoprel; Isoprenaline chloride;
Appearance: white crystalline powder
Molecular Weight: 247.72
Density: 1.324 g/cm3
Boiling Point: 417.5 °C at 760 mmHg
Melting Point: 165-175 °C (dec.)(lit.)
Flash Point: 179.7 °C
Storage Temperature: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Solubility: Soluble
Biological Activity: Standard selective β -adrenoceptor agonist; vasorelaxant and bronchodilator. Activation of β 2 receptors activates downstream PKA and ERK, and may stimulate NO-mediated endothelium-dependent smooth muscle relaxation. Active in vivo . Also available as part of the β -Adrenoceptor Agonist Tocriset™ and Mixed Adrenergic Tocriset™ .
Stability: Stable, but may be air and light sensitive. Incompatible with strong oxidizing agents.
Usage: Pharmaceutical.