| Product name |
Indometacine |
| CAS No. |
53-86-1 |
| Molecular Structure |
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| Uasage |
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EINECS: 200-186-5
Molecular Formula: C19H16ClNO4
Synonyms: indomethacin methanol solution; indomethacin crystalline; indomethacin usp; indometacin; 1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-ylacetic acid
Appearance: White crystalline powder
Molecular Weight: 357.79
Density: 1.32g/cm3
Boiling Point: 499.4 °C at 760 mmHg
Melting Point: 155-162℃
Flash Point: 255.8 °C
Storage Temperature: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Solubility: Insoluble
Biological Activity: Cyclooxgenase (COX) inhibitor; displays selectivity for COX-1 (IC 50 values are 230 and 630 nM for human COX-1 and COX-2 respectively). Widely used anti-inflammatory agent.
Stability: Stable. Incompatible with strong oxidizing agents.
Usage: Inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD
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