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Anastrozole

Product name	Anastrozole
CAS No.	120511-73-1
Molecular Structure
Uasage
Molecular Formula:C₁₇H₁₉N₅ Synonyms:10-Methoxy-5H-dibenz[b,f]azepine-5-carbonylchloride; 1,3-Benzenediacetonitrile,a,a,a',a'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)- (9CI); 2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]di(2-methylpropionitrile); 2-[3-(2-Cyano-2-propyl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropiononitrile; Asiolex; Anastrol; Appearance:crystalline solid Molecular Weight:293.37 Density:1.08 g/cm³ Boiling Point:469.7 oC at 760 mmHg Melting Point:81-82℃ Flash Point:469.7℃ at 760 mmHg Storage Temperature:Store in original container in a cool dark place. Refractive index:1.791 Solubility:Insoluble Biological Activity:Potent and highly selective aromatase (CYP19) inhibitor (IC 50 = 15nM) that has no discernible effect on adrenocorticoid hormone synthesis. Reduces plasma estrogen levels and exhibits antitumor activity in vivo . Orally active. Usage:An aromatase inhibitor. Used as an antineoplastic.

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