EINECS: 206-656-6
Molecular Formula: C₂₀H₃₂O₅
Synonyms: 5-Heptenoicacid, 7-[3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]- (8CI); (-)-Prostaglandin E2; (15S)-Prostaglandin E2; 11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (5Z,11a,13E,15S); 11a,15a-Dihydroxy-9-oxo-5-cis,13-trans-prostadienoic acid; Cervidil; Cerviprime; Dinoprostone; Enzaprost E; Minprositin E2; NSC 196514; PGE2; Primiprost; Prostaglandin E2; Prostenon; Prostenone; Prostin (prostaglandin); U 12062; Vivelle-Dot; l-Prostaglandin E2;
Appearance: White crystals.
Molecular Weight: 352.46508
Density: 1.148g/cm3
Boiling Point: 530.1°Cat760mmHg
Melting Point: 66-68 ºC
Flash Point: 288.5°C
Alpha: -85.5 º (C=1, C2H5OH)
Storage Temperature: −20°C
Solubility: insoluble
Biological Activity: Endogenous prostaglandin and primary product of arachidonic acid/cyclooxygenase pathway. Binds with high affinity to EP 1 , EP 2 , EP 3 and EP 4 receptors (K d values range between ~ 1-10 nM). Influences a wide range of processes including inflammation, smooth muscle relaxation, fertility and gastric mucosal integrity. Regulates vertebrate hematopoietic stem cell (HSC) homeostasis.
Stability: Stable under normal temperatures and pressures. Light sensitive.
Usage: The most common and most biologically potent of mammalian prostaglandins