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   BICALUTAMIDE

Product name	BICALUTAMIDE
CAS No.	90357-06-5
Molecular Structure
Uasage
Molecular Formula:C18H14F4N2O4S Synonyms:(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methyl-propanamide; Casodex; Propanamide, N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)sulfonyl)-2-hydroxy-2-methyl-, (+-)-; Bicalutamide (JAN/USP); Casodex (TN); (±)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-methyl-[(4- fluorophenyl) sulfonyl]-2-hydroxy- 2-methyl propanamide; N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-fluorophenylsulfonyl)-2-hydroxy-2-methylpropanamide; Bicalutamide [USAN:BAN:INN]; ICI 176334; Propanamide,N-[4-cyano-3-(trifluoromethyl)- phenyl]-3-[(4-fluorophenyl)sulfonyl]-2- hydroxy-2-methyl-; HS Code:29242995 Appearance:off-white crystalline solid Molecular Weight:430.373373 Density:1.52 g/cm3 Boiling Point:650.3 °C at 760 mmHg Melting Point:191-193℃ Flash Point:347.1 °C Storage Temperature:Store in original container in a cool dark place. Refractive index:1.577 Solubility:Insoluble in water Biological ActivityOrally active non-steroidal androgen receptor antagonist (IC 50 = 190 nM). Displays peripheral selectivity and does not effect serum levels of LH and testosterone. Exhibits potent anticancer activity in vivo . Usage:Non-steroidal peripherally active antiandrogen. Used as an antiandrogen, antineoplastic (hormonal)

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